I'm currently reading the Brian Lumley book The Clock of Dreams, one of the Titus Crow stories set in the Mythos.
Lumley's stuff is from the "Derleth School" of Cthulhu Mythos adventuring. That is to say, Lumley took to August Derleth's imposing of a Christian-like "good vs. evil" mentality upon the Elder Gods and The Great Old Ones. Die-hard fans of Lovecraft took exception to much of what Derleth did, including such minutea as his coining the phrase "Cthulhu Mythos (Lovecraft himself used the term "Yog-Sothothery"), but mostly for his creation of heroes who could take it to the grill of Lovecraftian monsters. They are not milquetoast academics who faint at the smell of a fart like most of Lovecrafts heroes. Guys like Crow, though outmatched, fight back against the slimey gods of the Mythos. Lumley said it best here:
I have trouble relating to people who faint at the hint of a bad smell. A meep or glibber doesn't cut it with me. (I love meeps and glibbers, don't get me wrong, but I go looking for what made them!) That's the main difference between my stories...and HPL's. My guys fight back. Also, they like to have a laugh along the way.
I have to admit that this is my favored type of character for Call of Cthulhu play, mostly because I prefer long campaigns. BTB CoC is not meant for long campaigns
Still, I take exception to the somewhat corney creation of entities such as Kthanid (pictured above), a brother of Cthulhu who is his twin, except for his crystal eyes. He is the "good" to Cthulhu's "evil," which I just find way to simplistic and far too Christian in concept. In The Clock of Dreams his is a helpful figure, and I have to admit I think a helpful monster should be pretty rare in The Mythos, no matter what flavor. And c'mon, a helpful brother of Cthulhu is just plain lame.
For my Cthulhu games, I like to find a kind of balance to the hopeless universe of Lovecraft. Sure, you may find a powerful friend here and there, but really, you need a mostly hopeless and terrifying universe to get the most juice out of this genre.